SEBIPROX ® - Ciclopirox

SEBIPROX ® is a drug based on Ciclopirox olamina

THERAPEUTIC GROUP: Antimycotics for topical use

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications SEBIPROX ® - Ciclopirox

SEBIPROX ® is indicated for the treatment of seborrheic dermatitis of the scalp.

Mechanism of action SEBIPROX ® - Ciclopirox

SEBIPROX ®, a medicine based on Ciclopirox, is successfully used in the treatment of dandruff and seborrheic dermatitis of the scalp.

Its therapeutic action in the aforementioned cases is due to the anti-fungal activity against Pityrasporum and Malassezia, microorganisms involved in the pathogenesis of seborrheic dermatitis of the scalp, performed through the biological mechanism that involves the chelation of heavy metals, including iron, important for cellular metabolism.

The anti-fungal action is supplemented by the antibacterial action directed against Gram-positive and Gram-negative bacteria which even more effectively supports the therapeutic properties of SEBIPROX ®.

The pharmacodynamic properties are further optimized by the pharmacokinetic properties which, by minimizing the systemic absorption of Ciclopirox, make the therapy safe and well tolerated.

Studies carried out and clinical efficacy

CICLOPIROX CLINIC

Drugs. 2010 Nov 12; 70 (16): 2133-52.

Very interesting Italian work that, over time, re-evaluating all the potential anti-fungal agents used for topical use, reaffirms the efficacy of Ciclopirox, underlining its wide clinical applications and its excellent tolerability.

CYCLOPIROX IN THE TREATMENT OF TINEA CAPITIS

Pediatr Dermatol. 2010 Sep-Oct; 27 (5): 459-62.

Study demonstrating the efficacy of Ciclopirox in shampoo in the treatment of ringworm of the scalp in young patients aged 1 to 11 years, even when compared to that of antifungals most commonly used in these cases.

EFFECTIVENESS OF THE CYCLOPIROX-BASED SHAMPOO IN THE TREATMENT OF SEBORRHEIC DERMATITIS OF SCALPELIN LEATHER

J Dermatolog Treat. 2007; 18 (2): 88-96.

Clinical trial conducted on approximately 350 patients demonstrating the greater efficacy of the Ciclopirox-based shampoo than that based on ketoconazole in the treatment of seborrheic dermatitis of the scalp.

Method of use and dosage

SEBIPROX ®

Shampoo with 1.5 g of Ciclopirox olamina per 100 g of product.

It is advisable to apply the appropriate amount of shampoo on the scalp two or three times a week, taking care to gently massage the region to obtain a generous foam to rinse off after 3-5 minutes.

Warnings SEBIPROX ® - Ciclopirox

The use of SEBIPROX ® must be justified by clinical needs preferably ascertained by your doctor.

The patient in therapy at the same time should put in place a series of hygienic-sanitary rules designed to optimize the therapeutic efficacy of the medicine by controlling the potential side effects.

Avoid contact of the shampoo with the eyes, thoroughly clean your hands after application carefully follow the instructions for use of the medicine are the main rules to be respected.

It should also be remembered that prolonged use of SEBIPROX ® could cause scalp irritation or hair discoloration.

It is advisable to keep the medicine out of the reach of children.

PREGNANCY AND BREASTFEEDING

Although there are no studies able to fully characterize the safety profile of Ciclopirox in fetal health shampoos, the low systemic absorption of the active ingredient could justify the use of SEBIPROX ® during pregnancy and in the subsequent breastfeeding period, as long as everything happens under the strict supervision of your doctor.

Interactions

Drug interactions worthy of clinical note are currently unknown.

Contraindications SEBIPROX ® - Ciclopirox

The use of SEBIPROX ® is contraindicated in patients who are hypersensitive to the active substance or to one of its excipients.

Undesirable effects - Side effects

The use of SEBIPROX ® is generally safe and well tolerated, although side effects such as erythema, itching and skin irritation of the scalp have sometimes been observed

Note

SEBIPROX ® is a non-prescription drug.

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